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How is the PAIRFS technology used in ZoneX and BikeX validated?

Sep 12
2 min read

The technology was validated in a clinical study conducted with the Grenoble University Hospital. This article details the principle and methodology.


A technology for measuring ventilatory thresholds

PAIRFS' first products are designed for sports professionals and athletes and allow for the measurement of ventilatory thresholds. The objective of the measurement is to determine the exercise intensities to which these thresholds correspond.


Training zones and thresholds. More info
Training zones and thresholds. More info

2.2x more progress with physiological zones

These key intensities then allow for the creation of highly effective training plans. In their 2015 article, Wolpern et al. [ ref ] show that with the same 3-month training plan, athletes who use ventilatory thresholds to determine effort intensities progress 2.2 times faster than those who use the cardiac reserve method.

ZoneX and BikeX are the only simple, reliable and accessible solutions that offer this type of gain.


How are the thresholds measured?

Training zone measurements are performed according to Wasserman 's method and Anselmi 's article . Thresholds are measured by detecting variations in two respiratory parameters:

  • VE: minute ventilation (L/min)

  • VE/VCO₂: ventilatory equivalent for CO₂


Theoretical variations
Theoretical variations
Examples of variations
Examples of variations

To measure the thresholds, it is therefore sufficient to ensure that the variations in ventilation and CO2 in the exhaled air are indeed proportional to those of the reference machines.


Procedure for a validation test

During a validation test, the guinea pig wears both gas exchange analysis systems:

  • The university hospital system (the white tube that comes out)

  • The PAIRFS system

  • And sensors used for stress testing: ECG, blood pressure monitor...


The reliability analysis is performed as follows:

  • The signals from both systems are synchronized based on the respiratory rhythm


Signals are synchronized using breath rythm
Signals are synchronized using breath rythm

  • The scaled ventilation and CO2 signals are then compared.



Ventilation signal at scale
Ventilation signal at scale

CO2 signals at scale
CO2 signals at scale

The results

Twenty people performed the stress test during the clinical trial. Both systems consistently showed a correlation as described above, with slope breaks occurring at the same location.

This study demonstrates that PAIRFS technology works as well as reference systems for determining ventilatory thresholds.


Some illustrations of respiratory signals are shown below:




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